SCI论文投稿cover-letter-投稿信模版

('SCI论文投稿coverletter投稿信模版DeareditorialboardofEuropeanJournalofCardiology,Pleasefindenclosedthemanuscript:“Theangiotensin-convertingenzymeisnotariskfactorformyocardialinfarctioninFrenchindividuals”,bySarahH.,etal.,tobesubmittedasaShortCommunicationtotheEuropeanJournalofNeurologyforconsiderationofpublication.Allco-authorshaveseenandagreewiththecontentsofthemanuscriptandthereisnofinancialinteresttoreport.Wecertifythatthesubmissionisoriginalworkandisnotunderreviewatanyotherpublication.Inthismanuscript,wereporttheresultsofthefirststudyonthegeneticandfunctionalrolesoftheACEontheriskofsufferingamyocardialinfarctionintheFrenchpopulation.Indeed,wegenotypedthers4341polymorphismin531IScasesand549healthycontrols,andthenperformedfunctionalstudiesbymeasuringserumACEproteinlevelandactivityinhealthycontrols,strokepatientsatbaselineandstrokepatients24hafterstrokesymptomsonset.TheresultsfromourstudydidnotrevealanyassociationoftheACEvariantwithmyocardialinfarction,althoughitaffectedACEproteinlevel,andischemicstrokepatientsshowedlowerACElevelthancontrolsintheacutephasebutnotinthechronicphase.WebelievethatourfindingscouldbeofinteresttothereadersofEuropeanJournalofCardiologybecausetheybringnewandstrongevidencethattheACEgeneandproteinarenotariskfactorformyocardialinfarction.Wehopethattheeditorialboardwillagreeontheinterestofthisstudy.Sincerelyyours,SarahH.onbehalfoftheauthors.Correspondingauthor:SarahHamiltonatCardiovascularResearchLaboratory,MarieCurieResearchInstitute,75000,Paris,France,xxx@mariecurie.fr,phonenumber:+33582246xxx,faxnumber:+33582246xxx.Case1DearEditor,Wewouldliketosubmittheenclosedmanuscriptentitled"GDNFAcutelyModulatesNeuronalExcitabilityandA-typePotassiumChannelsinMidbrainDopaminergicNeurons",whichwewishtobeconsideredforpublicationinNatureNeuroscience.GDNFhaslongbeenthoughttobeapotentneurotrophicfactorforthesurvivalofmidbraindopaminergicneurons,whicharedegeneratedinParkinson’sdisease.Inthispaper,wereportanunexpected,acuteeffectofGDNFonA-typepotassiumchannels,leadingtoapotentiationofneuronalexcitability,inthedopaminergicneuronsincultureaswellasinadultbrainslices.Further,weshowthatGDNFregulatestheK+channelsthroughamechanismthatinvolvesactivationofMAPkinase.Thus,thisstudyhasrevealed,forthefirsttime,anacutemodulationofionchannelsbyGDNF.OurfindingschallengetheclassicviewofGDNFasalong-termsurvivalfactorformidbraindopaminergicneurons,andsuggestthatthenormalfunctionofGDNFistoregulateneuronalexcitability,andconsequentlydopaminerelease.TheseresultsmayalsohaveimplicationsinthetreatmentofParkinson’sdisease.Duetoadirectcompetitionandconflictofinterest,werequestthatDrs.XXXofHarvardUniv.,andYYofYaleUniv.notbeconsideredasreviewers.Withthanksforyourconsideration,IamSincerelyyours,case2DearEditor,Wewouldliketosubmittheenclosedmanuscriptentitled"Ca2+-bindingproteinfrequeninmediatesGDNF-inducedpotentiationofCa2+channelsandtransmitterrelease",whichwewishtobeconsideredforpublicationinNeuron.WebelievethattwoaspectsofthismanuscriptwillmakeitinterestingtogeneralreadersofNeuron.First,wereportthatGDNFhasalong-termregulatoryeffectonneurotransmitterreleaseattheneuromuscularsynapses.Thisprovidesthefirstphysiologicalevidenceforaroleofthisnewfamilyofneurotrophicfactorsinfunctionalsynaptictransmission.Second,weshowthattheGDNFeffectismediatedbyenhancingtheexpressionoftheCa2+-bindingproteinfrequenin.Further,GDNFandfrequeninfacilitatesynaptictransmissionbyenhancingCa2+channelactivity,leadingtoanenhancementofCa2+influx.Thus,thisstudyhasidentified,forthefirsttime,amoleculartargetthatmediatesthelong-term,synapticactionofaneurotrophicfactor.Ourfindingsmayalsohavegeneralimplicationsinthecellbiologyofneurotransmitterrelease.Sincerelyyours,Case3SampleCoverLetter[theexampleusedistheIJEB]DearEditorofthe[pleasetypeinjournaltitleoracronym]:Enclosedisapaper,entitled"MobileAgentsforNetworkManagement."Pleaseacceptitasacandidateforpublicationinthe[journaltitle].Belowareourresponsestoyoursubmissionrequirements.1.Titleandthecentralthemeofthearticle.Papertitle:"MobileAgentsforNetworkManagement."Thisstudyreviewstheconceptsofmobileagentsanddistributednetworkmanagementsystem.Itproposesamobileagent-basedimplementationframeworkandcreatesaprototypesystemtodemonstratethesuperiorperformanceofamobileagent-basednetworkovertheconventionalclient-serverarchitectureinalargenetworkenvironment.2.Whichsubject/themeoftheJournalthematerialfitsNewenablingtechnologies(ifnomatchingsubject/theme,enter\'Subjecthighlyrelatedto[subjectofjournal]butnotlistedby[pleasetypeinjournaltitleoracronym])3.Whythematerialisimportantinitsfieldandwhythematerialshouldbepublishedin[pleasetypeinjournaltitleoracronym]?Thenecessityofhavinganeffectivecomputernetworkisrapidlygrowingalongsidetheimplementationofinformationtechnology.Findinganappropriatenetworkmanagementsystemhasbecomeincreasinglyimportanttoday\'sdistributedenvironment.However,theconventionalcentralizedarchitecture,whichroutinelyrequeststhestatusinformationoflocalunitsbythecentralserver,isnotsufficienttomanagethegrowingrequests.Recently,anewframeworkthatusesmobileagenttechnologytoassistthedistributedmanagementhasemerged.Themobileagentreducesnetworktraffic,distributesmanagementtasks,andimprovesoperationalperformance.Giventoday\'sbandwidthdemandovertheInternet,itisimportantforthe[journaltitle/acronym]readerstounderstandthistechnologyanditsbenefits.Thisstudygivesareal-lifeexampleofhowtousemobileagentsfordistributednetworkmanagement.Itisthefirstintheliteraturethatreportstheanalysisofnetworkperformancebasedonanoperationalprototypeofmobileagent-baseddistributednetwork.Westronglybelievethecontributionofthisstudywarrantsitspublicationinthe[journaltitle/acronym].4.Names,addresses,andemailaddressesoffourexpertreferees.Prof.Dr.WilliamGatesChairProfessorofInformationTechnology321JohnsonHallPremierUniversityLancaster,NY00012-6666,USAphone:+1-888-888-8888-fax:+1-888-888-8886e-mail:wgates@lancaster.eduExpertise:publishedarelatedpaper("TCP/IPandOSI:FourStrategiesforInterconnection")inCACM,38(3),pp.188-198.Relationship:ImetDr.Gateonlyonceataconferencein1999.Ididn\'tknowhimpersonally.AssocProf.Dr.JohnAdamsDirectorofNetworkResearchCenterCollegeofBusinessAustralianUniversity123,HarborDriveSydney,Australia56789phone:+61-8-8888-8888-fax:+61-8-8888-8886e-mail:jadams@au.edu.auExpertise:publishedarelatedpaper("CreatingMobileAgents")inIEEETOSE,18(8),pp.88-98.Relationship:None.IhavenevermetDr.Adams.AssocProf.Dr.Chia-HoChenChairofMISDepartmentCollegeofManagementOpenUniversity888,PutongRoadKeelung,Taiwan100phone:+886-2-8888-8888-fax:+886-2-8888-8886e-mail:chchen@ou.edu.twExpertise:publishedarelatedpaper("NetworkManagementforE-Commerce")inIJElectronicBusiness,1(4),pp.18-28.Relationship:Formerprofessor,dissertationchairman.Mr.FrankYoungPartner,ABCConsulting888,SeashoreHighwayWonKok,KowloonHongKongphone:+852-8888-8888-fax:+852-8888-8886e-mail:fyoung@abcc.comExpertise:Mr.Youngprovidesconsultingservicesextensivelytohisclientsregardingnetworkmanagementpractices.Relationship:IhaveworkedwithMr.Younginseveralconsultingprojectsinthepastthreeyears.Finally,thispaperisouroriginalunpublishedworkandithasnotbeensubmittedtoanyotherjournalforreviews.Sincerely,JohnnySmith',)